[HD] Story of a Dot Online Schauen



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Naomi Levine







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Bekanntmachung : 1971-06-06
Länge : 2 Minutes
Gattung :
Firma :

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Testisdetermining factor Wikipedia ~ Testisdetermining factor TDF also known as sexdetermining region Y SRY protein is a DNAbinding protein also known as generegulatory proteintranscription factor encoded by the SRY gene that is responsible for the initiation of male sex determination in therian mammals placental mammals and marsupials SRY is an intronless sexdetermining gene on the Y chromosome

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SOX9 Wikipedia ~ 20682 Ensembl ENSG00000125398 ENSMUSG00000000567 UniProt P48436 Q04887 RefSeq mRNA NM000346 NM011448 RefSeq protein NP000337 NP035578 Location UCSC Chr 17 7212 – 7213 Mb Chr 11 11278 – 11279 Mb PubMed search Wikidata ViewEdit Human ViewEdit Mouse Transcription factor SOX9 is a protein that in humans is encoded by the SOX9 gene Contents 1 Function 2 Clinical significance

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Swyer syndrome NORD National Organization for Rare ~ The SRY gene is believed to be critical in initiating male sex determination by triggering undifferentiated gonadal tissue to transform into testes Absence or mutation of this gene results in the failure of the testes to form Since only 1520 percent of women with Swyer syndrome have a mutation of the SRY gene researchers believe that defects involving other genes can also cause the

6662 Gene ResultSOX9 SRYbox transcription factor 9 ~ The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMGbox class DNAbinding proteins It acts during chondrocyte differentiation and with steroidogenic factor 1 regulates transcription of the antiMuellerian hormone AMH gene Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia frequently with sex reversal